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2.1.2 Iron transport in brain Iron is an essential cofactor for many metabolic processes in the central nervous system (CNS), including DNA synthesis in neurons, oxidative phosphorylation, neurotransmitter production and oxygen transport ( Figure 2 )

doi: 10.3389/fmicb.2025.1589946 Received 08 March 2025 Accepted 29 May 2025 Published 01 July 2025 Volume 16 - 2025 Edited by Jun Zhou, Shandong First Medical University, China Reviewed by Yun Peng Fan, Northwest A&F University, China Chuanmin Ma, Jinan Center for Disease Control and Prevention, China Ziming Wang, Hospital of Chengdu University of Traditional Chinese Medicine, China Yong Wang, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, China Updates Copyright 2025 Li, Chen, Xu, Li and Li

Several clinical trials and meta-analyses have assessed the effects of vitamin D supplementation on IR and glucose metabolism in women with PCOS

Its transport is Na-and pH-dependent, however it does not require Cl ions

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