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To discern p53-dependent and independent effects of APR-246 and a potential role of germline SNP at codon 72 in modifying these effects, we utilized three p53-null ovarian cancer cell lines expressing inducible R175H mutant with either P72 or R72 SNP

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Common neurotransmitters in the retina are glutamate, GABA, glycine, dopamine, and acetylcholine