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Inside hepatocytes, it immediately begins neutralizing free radicals and binding to toxins

Dopaminergic neurons are particularly susceptible to oxidative stress due to the metabolism of dopamine

20 Primarily, NADPH provides reducing equivalents for fatty acid synthase (FASN), the main rate-limiting enzyme, to synthesize fatty acids with acetyl-CoA serving as a primer and malonyl-CoA as a two-carbon donor, 21,22 and provides the needed electrons for ironsulfur (Fe/S) protein assembly that participate in non-essential amino acid biosynthesis and lipoic acid synthesis, tRNA modification, DNA replication and repair, and telomere maintenance

These particles are capable of co-delivering photosensitizers (such as protoporphyrin IX) and chemotherapeutic agents (such as doxorubicin), using transferrin for tumor-specific targeting and hemoglobin as an internal oxygen source (Zhu et al., 2024)

Front Nutr 8:638740