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Previous targeting of the HSP90 family of chaperones, to which TRAP1 belongs, has been pursued with the drug IPI-504 which, in combination with the mTOR inhibitor rapamycin, cooperates in the growth repression of NF1 mutant cancer cells [36]

Liproxstatin-1 (Lip-1), bearing a spiroquinoxaline amine scaffold, is efficacious in neurological disorders and cancers by inhibiting lipid peroxidation [61]

Overall, chamomile is considered a safe and effective herbal intervention for managing stress, anxiety, and associated psychological symptoms (Khalesi et al., 2019)

Shao S, Zou Y, Kennedy KG, Dimick MK, Andreazza AC, Young LT, et al

V284I mutation in the enzyme gentisate 1,2-dioxygenase I in lower eukaryotes leads to superior enzyme function, up to 260% [77]