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Cagrilintide's gastric-slowing effect peaks 90-120 minutes post-dose and lasts 6-8 hours

[DOI] [PMC free article] [PubMed] [Google Scholar] 342.Cha, Y

Both compounds delay gastric emptying through different pathways, and the additive effect can produce nausea severe enough to derail otherwise compliant patients

The approval is based on the Phase III JUPITER-02 study where Loqtorzi combined with chemotherapy significantly improved progression-free survival, reducing the risk of disease progression or death by 48% compared to chemo alone

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