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10.2147/DDDT.S284163 103 XingweiX.XinG.PengZ.TaoF.BowenD.XiaomingK.et al (2014)

The mechanistic literature on GHK-Cu in primary human dermal fibroblasts and skin-explant models has typically used GHK-Cu concentrations in the nanomolar to low-micromolar range, with biological effects on collagen synthesis, fibroblast proliferation, and gene expression reported at sub-toxic concentrations

We speculate that the BPC157-FBXO22 interaction via P3 delays enzymatic degradationpeptide catabolism typically initiates with endopeptidases, followed by stepwise proteolysis into amino acids

Ferritin, typically found in the cytosol can also be secreted, providing an additional iron source

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