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Pregnant women should be sure to get folate from a supplement to help avoid birth defects, and people with genetic mutations affecting the MTHFR enzyme may benefit from a form of folate known as methylfolate

Methods: As a part of a larger observational study, demographic, clinical, and social data were collected

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While this treatment approach is sufficient to correct for peripheral symptoms such as anemia, the accompanying neurological defects are not easily addressed since patients require supraphysiological folate concentrations in blood to be able to increase CSF folate

Focal adhesion kinase [pY861] is also crucial for RAS-mediated transformation of fibroblast (Lim et al, 2004)