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Reduced intestinal blood perfusion, mesenteric ischemia, and decreased bowel movements caused by cirrhosis have appeared to change the normal microenvironment to be less suitable for beneficial populations of Bacteroides and Clostridium , resulting in invasion and colonization of opportunistic pathogens, such as Enterobacteriaceae and Veillonella

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These animals were housed under a controlled 12:12-hour lightdark cycle and provided unrestricted access to food and water throughout the experimental timeline [2]