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Simic P, Zainabadi K, Bell E, Sykes DB, Saez B, Lotinun S, et al

R.WangC

The cholesterol required for steroid hormone synthesis can be theoretically obtained from several different potential sources including de novo synthesis from acetate, cholesteryl esters stored in the form of lipid droplets or can be obtained from circulating lipoproteins via low-density lipoprotein (LDL) receptor/endocytic pathway or SR-BI (for high-density lipoprotein or HDL)/selective uptake pathway [3, 4]