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As -cells are intrinsically susceptible and constantly exposed to ER stress owing to an intense trafficking of proinsulin to the ER due to high demand for insulin production and secretion in response to dietary nutrient stimulation, chronic supra-physiological ER stress in -cells alters the UPR signaling that eventually leads to -cell demise and diabetes

Metallothionein I + II expression and their role in experimental autoimmune encephalomyelitis

Peptides are short chains of amino acids , typically consisting of 250 amino acids linked by peptide bonds

the propionyl-L-carnitine free base is reacted with nitric acid at a temperature of between 30 C

Treatment efficacy is often dependent on the type and depth of each scar and the state of the underlying tissue