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1498, 5776 10.1111/nyas.14669 [DOI] [PMC free article] [PubMed] [Google Scholar] 96.Harel Y., Zuk L., Guindy M., Nakar O., Lotan D

While it is generally accepted that opioid withdrawal is not fatal, iatrogenic precipitated withdrawal may be much more severe resulting in clinically significant autonomic hyperactivity with consequences such as pulmonary edema and make patients more reticent to continue with future medication for opioid use disorder