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Description

5-Amino-1MQ is a small-molecule NNMT enzyme inhibitor

References 1 MillerKASiegelRLLinCCSmithABKramerJSRowlandJHet al

LiGLinYZhangYGuNYangBShanSet al

The isolation of phenolics and flavonoids from this plant may offer potential candidates for the prevention of chronic diseases [52, 53]

However, the dual activity of KYNA, antagonizing NMDARs and 7nAChRs both of which are critical for normal brain function complicates pharmacological targeting, as achieving therapeutic modulation within an optimal window risks unintended and potentially severe side effects