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We stated in the CY 2026 OPPS/ASC proposed rule that it was unclear to us whether the aprevo Cervical ACDF system and the aprevo Cervical ACDF-X system (with and without CAM) are different devices such that they should be evaluated separately for OPPS pass-through payment status

In mammals, biotin is a coenzyme of four major carboxylases (pyruvate carboxylase, propionyl coenzyme A carboxylase, 3-methylcrotonyl coenzyme A carboxylase, and acetyl coenzyme A carboxylase)

doi: 10.1159/000350379

The matrix scaffold provides a supportive structure for cells to grow in the correct shape and orientation

For optimal results, consult a healthcare practitioner before use