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For example, the phrase treating a patient with a disease or disorder caused or characterized by excess weight may reduce the severity of the disease or disorder to such a degree that the subject no longer experiences discomfort and/or altered function

Once thyroid function is stable, thyroid function tests are typically performed annually, but more frequent testing is warranted during active weight loss

HIF targets include genes encoding mediators of angiogenesis such as vascular endothelial growth factor (VEGF) and VEGF receptors, enzymes of the glycolytic pathway such as hexokinase 2, lactate dehydrogenase, and glucose transporters (GLUT-1, GLUT-3), as well as CA IX

The only difference is concentration