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Treatment of NTS with inhibitors 1, 2, 4, 7 , and 8 , positive control AF, or negative control 12 for 2 h was followed by addition of TRFS-Green

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Furthermore, preclinical data help determine optimal dosing and duration of SFN administration, as well as identifying potential biomarkers for response, such as reduced inflammatory markers or improved mitochondrial function

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These channels are the mediators of intrinsic neuronal excitability and are responsible for the generation and propagation of action potential (Kwong and Carr, 2015)