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Therefore, it is essential to accurately control and study the molecular mechanism of drug resistance in different types of cancer cell lines and to enhance the sensitivity of combination drugs

We provide evidence for lysine acetylation of SnCE1, regulating its oligomeric state

ABC transporters also show high expression levels in tissues involved in excretion/detoxification (e.g., liver and kidneys), or acting as barriers (gut epithelium, capillary endothelia forming the blood-brains barrier, epithelial cells...) mediating the cellular efflux of a diverse array of chemicals and some metals and limiting chemical uptake