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Description

The FDA nod is based on the Phase III GENESIS trial, which compared Aphexda plus filgrastim against placebo plus filgrastim

The mental health claims are extrapolations from animal data and mechanistic speculation

doi: 10.1038/s41413-023-00280-x

The compound reduces plasma creatine kinase levels (a marker of muscle damage) and decreases malondialdehyde concentration (indicating reduced lipid peroxidation) in exercised muscle tissue