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Research on COPD endotypes is advancing rapidly, and several specific endotypes have been proposed or identified, including the T2-low endotype (neutrophil-predominant), T2-high endotype (eosinophil-predominant), genetic endotypes (1-antitrypsin deficiency endotype, telomerase gene mutation endotype), pulmonary vascular endotype, and persistent inflammation/autoimmune endotype ( Phenotypes represent the external clinical manifestations of COPD, while endotypes provide mechanistic explanations behind these manifestations, thus linking clinical observations to molecular pathogenesis

Three-dimensional-printed polycaprolactone/polypyrrole conducting scaffolds for differentiation of human olfactory ecto-mesenchymal stem cells into Schwann cell-like phenotypes and promotion of neurite outgrowth

A mini barrel is located between the dimerization unit and the edge of the antiparallel sheet unit

Firstly, the permeability of EBA increased after 24-h incubation with 3-PLG-ibu, and secondly, in inflammatory condition besides the 3-PLG-ibu-A-GSH the free ibuprofen treated group also significantly strengthened the integrity of the BBB model for the bigger transcellular marker molecule (Fig

Evaluation of the 5'-flanking regions of murine glutathione peroxidase five and cysteine-rich secretory protein-1 genes for directing transgene expression in mouse epididymis