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3.5 Meta-analysis The included studies showed substantial heterogeneity (I 2 = 99.6%, p 0.05), supporting the conclusion of comparable efficacy and the lack of a clear doseresponse relationship

However, microneedling + PRP is also being studied as a promising combination, and some clinicians use all three approaches together for maximum benefit

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When glutathione is depleted, mitochondrial function can decline, leading to symptoms like fatigue, muscle weakness, and poor exercise tolerance