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Decreased inflammation and bacterial load: L-GSH, in combination with PZA and INH, significantly reduced the bacterial load in granulomas, particularly in BCG-vaccinated individuals

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LC-MS/MS using 10plex TMT proteomics Sample preparation Pulverized liver tissue (20 mg aliquot) were homogenized in lysis buffer (8 M urea, 50 mM TEAB (triethyl ammonium bicarbonate), pH 8) followed by sonication (at level 5

In a recently completed phase 2 trial (abstract data), 46 weeks of survodutide once weekly (0.6 to 4.8 mg) resulted in a dose-dependent mean WL up to 18.7% vs

10.1016/j.mam.2018.06.002 11 GongX.DuanY.WangY.YeZ.ZhengJ.LuW.et al (2020)