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Higher baseline mucus plug scores correlate with larger improvements in FEV 1 and asthma control after biologic treatment, suggesting that baseline mucus burden predicts response to biologic therapy [47]

doi: 10.1016/j.abb.2010.07.012 60 AwadASRouseMDKhutsishviliKHuangLBoltonWKLynchKRet al

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Berberine, a mitochondrial-targeting compound, can inhibit PINK1 promoter hypermethylation and enhance PINK1 expression, thereby promoting autophagy-lysosome pathway and alleviating mitochondrial dysfunction in AD models (Wang et al., 2023)

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