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In a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced Parkinsons disease mouse model, treatment with Lf-ASX-LPs resulted in 5.0-, 3.1-, and 5.6-fold increases in dopamine levels, TH + fiber density, and TH + neurons, respectively, restoring dopaminergic neuron damage

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10.1371/journal.pone.0228568 PLoS One 116 RuffinM.MercierJ.CalmelC.MesineleJ.BigotJ.SutantoE

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Lactobacillus paracasei modulates LPS-induced inflammatory cytokine release by monocyte-macrophages via the up-regulation of negative regulators of NF-kappaB signaling in a TLR2-dependent manner