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Naltrexone Naltrexone is an opioid receptor antagonist

Oncogenic RAS isoforms show a hierarchical requirement for the guanine nucleotide exchange factor SOS2 to mediate cell transformation

In contrast, probiotic intervention antagonizes ferroptosis through mechanisms such as reducing inflammation, repairing intestinal barrier, releasing antimicrobial peptides (cAMPs), regulating iron overload, and inhibiting lipid peroxidation (182, 183), thereby ameliorating the pathological phenotype of IBD ( Figure 3 )

The resulting p -values were corrected for multiple comparisons via the BenjaminiHochberg procedure