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To further test whether the incorporation of a targeting motif could enhance the binding of chimeric peptides in vivo , we used smearing FITC-peptides at the mouse back for 24 h and tracked the peptide location of the skin slices by fluorescent microscopy

The most commonly reported (10%) solicited adverse reactions in MenACWY conjugate vaccine-experienced individuals aged 15 through 25 years after Dose 1 and Dose 2, respectively, were pain at the injection site (80% and 74%), headache (41% and 33%), fatigue (40% and 33%), myalgia (15% and 13%), and nausea (15% and 12%) For BEXSERO, the most commonly reported (10%) solicited adverse reactions in a Phase 3 clinical trial were pain at the injection site (87%-92%), fatigue (45%-49%), headache (37%-41%), nausea (11%-13%), erythema (10%-15%), myalgia (10%-14%), and swelling (10%-14%) Common solicited adverse reactions with MENVEO among children initiating vaccination: at 2 months of age and receiving the four-dose series were tenderness and erythema at injection site, irritability, sleepiness, persistent crying, change in eating habits, vomiting, and diarrhea

Bussolati, B., Grange, C

Wright SL, Kelly FJ

Special attention should also be taken to ensure that the container is tightly sealed after use, as this will help prevent contamination and keep the water sterile