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ERS activating unfolded protein reaction (UPR) pathways is recognized by 3 sensors in endoplasmic reticulum (ER) membrane: protein kinase RNA-like endoplasmic reticulum kinase (PERK), inositol-requiring protein 1 (IRE1), and cyclic AMP-dependent transcription factor 6 (ATF6)

The diverse and dynamic phenotypes of reactive astrocyte reflect their context-dependent heterogeneity and adaptive capacity, which enables structural, molecular and functional adaptations to shifting physiological conditions and pathological insults

Genetically encoded fluorescent indicator for imaging NAD(+)/NADH ratio changes in different cellular compartments

Vitamin B9 (folic acid) may help slow the effects of age on memory and lessen the chance of Alzheimers disease

NVC was compared between individuals with and without stroke history, as well as those with varying degrees of SVD markers