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Its therapeutic potential also derives from multitarget mechanisms

He also operates his own center, New Life Cancer Centre, where he provides comprehensive cancer care

Vandenabeele P, Galluzzi L, Vanden Berghe T, Kroemer G

However, while BPC 157 has been marketed online and has gained attention through patents and anecdotal reports, it has not yet been approved by major medical regulatory bodies like the FDA, mainly due to the lack of human clinical trials

This is consistent with Trp1145 having a key role at the M-heat1FAT interface of the active state but not the intermediate TOPBP1-bound states (Extended Data Fig