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TB-500 considerations: Animal studies found TB-500 could accelerate dormant tumor growth and affect immune responses

Stogsdill JA, Ramirez J, Liu D, Kim YH, Baldwin KT, Enustun E, et al

The famous ~seven orders of magnitude (ten-million-fold) more potent than BDNF figure comes from a single in-vitro spine-counting assay comparing two molecules that signal through entirely different receptors