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10.3389/fmicb.2022.835677 32 CazzanigaG.ZambraM.BongioloS.PrpiH.FasolaE.ArrigoniF.et al (2025)

Epithalon has been investigated as a potential treatment for rheumatoid arthritis and ulcerative colitis due to its ability to regulate biomolecules involved in the inflammation process, such as cytokines and C-reactive protein

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373 In fact, when BMSCs are exposed to exendin-4, the expression of genes related to bone development factors such as Runx and Osterix, as well as genes responsible for producing the bone matrix such as Balp and Bglap, is upregulated

Instead, some adverse effects provoked by the exposures to isolated or binary combinations were not present in the ternary combinations, suggesting an antagonistic interaction ( 3 Future perspectives and conclusion Figure 1 summarizes the risks and perspectives on the use of pesticides in the Brazilian agricultural scenario