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15 Epidemiological studies have indicated that KOA affects about 654 million people worldwide, specifically affecting the elderly population over 45 years old (30%)

Phenolic fraction extracted from Kedrostis foetidissima leaves ameliorated isoproterenol-induced cardiotoxicity in rats through restoration of cardiac antioxidant status

Toxicology (2015) 334:94103

The amino acids are identified as V=valine

Hz and AcHz are thought to be further oxidized to reactive metabolites and involved in INH hepatotoxicity13, 16, 28, 56, 57, which was proposed to be mediated by microsomal P450s, especially CYP2E56, 58