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Cancer Res 79(18):45574567

Glutathione depleting drugs, antioxidants and intestinal calcium absorption

236 YeohBSAguilera OlveraRSinghVXiaoXKennettMJet al

Cytokine storms and pneumonia may be increased as a result of the deregulation of ACE-2 induced by SARS-CoV-2, and blocking the upstream regulation mir-125b-5p could provide a novel strategy to manage COVID-19 (Figure 6) (Morassi et al., 2020)

Interestingly, the decrease of ATP levels was delayed after the disappearance of dehydrogenase activity in 1 mM PAP-CYS treated cells perhaps implying a preservation of ATP levels even after impairment of intramitochondrial dehydrogenases activity for a limited time