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Description

The accumulation of ROS and the release of HSP70 induce oxidative stress, exacerbate innate immune activation, inflammation, and melanocyte apoptosis

By wrapping the glutathione in these lipids, we protect it from the harsh environment of the stomach

Chiang AC, Massague J

These variables, which often differ widely across studies, likely contribute to the heterogeneity observed in outcomes and may restrict the generalizability of results

HFD was initially employed to cause insulin resistance, followed by the administration of a low dose of STZ to selectively destroy pancreatic -cells, which are the primary source of insulin within the islets of Langerhans