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In addition, it showed GSH-dependent high cytotoxicity on account of the rapid exhaust of intracellular GSH by both GSH depletion and biosynthesis inhibition

Mortality deconvolution showed that the increase in overall (P + p) lifespan by GSH was solely attributable to reduced %P (Fig

Neurology 95 , e3012e3025 (2020)

In adult IBD patients, SQOR expression in the rectum and ascending colon is downregulated by 50% and 23%34%, respectively, compared to healthy individuals

used autoinducer-2 to enhance the expression of tight inducer protein to reduce intestinal damage (Sun et al., 2024), maintain water and electrolyte balance, reduce intestinal peristalsis and other measures also help improve intestinal barrier damage