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2020 safety paper is considered essential reading for any researcher evaluating this compounds translational potential

Mitochondrial dynamics play a crucial role in cellular homeostasis and include various aspects of mitochondrial function, including morphology, distribution, turnover, and quality control mechanisms such as mitophagy

Historically, the obesity pharmacotherapy literature notes early trial signals and also that development was terminated after failure to show meaningful weight loss in a larger, longer trial (as summarized in a peer-reviewed review discussing a 12-week signal and a later 24-week negative result)

1 (HPLC profile)