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AOD9604 also inhibited an enzyme called acetyl-CoA carboxylase, which is involved in making new fat

In further embodiments, the invention encompasses a method of modulating stem cell differentiation by contacting a stem cell expressing NNMT with one or more cations of the invention and with one or more cations chosen from Tables 3a and 3b

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Inhibit lipogenesis the metabolic process that forms fat (even from nonfat foods), which increases the amount of triglycerides in the body

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