In conclusion, GLA-mutant kidney organoids derived from human iPSCs are valuable tools for studying the mechanisms and developing novel therapeutic alternatives for Fabry disease
Each peptide is synthesized from pharmaceutical-grade amino acids, purified, freeze-dried, and packaged in sterile conditions for consistent particle size and solubility
The HAM/TSP treatment is limited to symptomatic therapy
Under the catalysis of nuclear receptor coactivator 4 (NCOA4) and microtubule-associated protein 1 light chain 3B (LC3B), large amounts of ferrous iron is released by ferritin through ferritinophagy, and enforce the vulnerability to ferroptosis (Cai et al., 2023

Measures of psoriatic arthritis: tender and swollen joint assessment, psoriasis area and severity index (PASI), nail psoriasis severity index (NAPSI), modified nail psoriasis severity index (mNAPSI), Mander/Newcastle enthesitis index (MEI), Leeds enthesitis index (LEI), spondyloarthritis research consortium of Canada (SPARCC), Maastricht ankylosing spondylitis enthesis score (MASES), Leeds dactylitis index (LDI), patient global for psoriatic arthritis, dermatology life quality index (DLQI), psoriatic arthritis quality of life (PsAQOL), functional assessment of chronic illness Therapy-Fatigue (FACIT-F), psoriatic arthritis response criteria (PsARC), psoriatic arthritis joint activity index (PsAJAI), disease activity in psoriatic arthritis (DAPSA), and composite psoriatic disease activity index (CPDAI)