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Mann et al., 2016[84])

C.SergushichevA.LampropoulouV.IvanovaY.LoginichevaE.et al (2015)

doi: 10.1007/s10555-007-9066-y 82 FengXLiXLiuNHouNSunXLiuY

On this basis, we further investigated the impact of c-Myc suppression on GGCT expression, and the results showed a significant reduction in GGCT protein levels (Fig

It reduced AGEs and receptor for advanced glycation end products (RAGE) expression, enhanced antioxidant enzyme activities (SOD, CAT, GSH-Px, T-AOC), and downregulated reduced the accumulation of AGEs and the expression of RAGE, increased activities of antioxidant enzymes (SOD, CAT, GSH-Px, T-AOC), and decreased levels of pro-inflammatory cytokines (TNF-, IL-1, IL-6) in a dose-dependent manner