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Il est impliqu dans les mtastases phthtases et le mtabolisme de l'acide folique, favorisant la transition du ttrahydrofolate de 5-mthyle en acide ttrahydrofluolique

A 26-week diabetes study measured human activity at 1 mg, but its endpoint was blood sugar rather than long-term weight. A short outpatient cohort measured about 4.7% weight loss over four weeks at 2.5 mg. Below 1 mg, estimates rely on pharmacokinetics and mechanism

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