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We propose that IOP elevation initiates hypoxia that contributes to mitochondrial dysfunction, oxidative stress, impaired mitophagy and inflammation and that these processes are exacerbated by interactions between inflammation and mitochondrial dysfunctional (Figure 1)

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Curcumins oxidative properties enable it to scavenge ROS in vivo , conferring antioxidant activity in normal cells ( FIGURE 4 The solubility and stability of curcumin depend on the type of solvent and pH level

Zinc and folic acid are matched at 15 mg and 400 g

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