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j , ChP validation showing altered TIMP3 ligandability in cells expressing the phosphorylation-deficient TACE-S791A mutant

The temperature-death risk relationships tend to be U-shaped or J-shaped where they reach a minimum at some optimal temperature (solid vertical black line), and the death rate increases as daily temperatures get significantly colder or warmer than the optimum

Furthermore, inhibition rate for SYP-14288 against X19-7 was 61.0% in the presence of DEM, which was much higher than SYP-14288 treatment alone with inhibition rate of 39.4% (Figure 4A)

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Provenzano M, Coppolino G, Faga T, Garofalo C, Serra R, Andreucci M