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healthy-adult study established that the albumin-binding version produces sustained, dose-dependent GH and IGF-I elevation, with a multi-day half-life

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10.1007/s11010-016-2885-9 288 SattlerR.XiongZ.LuW

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Finally, most studies evaluate the crude extract, which prevents the complete elucidation of molecular mechanisms of action and synergism between active metabolites (such as triterpenoids and flavonoids), limiting the development of optimized phytotherapeutic therapies (Table 3)