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Therefore, in view of current medical requirements, herein we have discussed effective therapeutic approaches and pharmacological interventions selectively targeting the molecular activation of fibroblasts during fibrosis which warrant further investigations

Amaria RN, Reddy SM, Tawbi HA, Davies MA, Ross MI, Glitza IC, Cormier JN, Lewis C, Hwu WJ, Hanna E, Diab A, Wong MK, Royal R, Gross N, Weber R, Lai SY, Ehlers R, Blando J, Milton DR, Woodman S, Kageyama R, Wells DK, Hwu P, Patel SP, Lucci A, Hessel A, Lee JE, Gershenwald J, Simpson L, Burton EM, Posada L, Haydu L, Wang L , Zhang S, Lazar AJ, Hudgens CW, Gopalakrishnan V, Reuben A, Andrews MC, Spencer CN, Prieto V, Sharma P, Allison J, Tetzlaff MT, Wargo JA

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Coenzyme Q10 decreases amyloid pathology and improves behavior in a transgenic mouse model of Alzheimer's disease

Samples were withdrawn regularly throughout the cultivations that were performed in duplicate, centrifuged and the supernatants were filtered through 0.2 m nylon syringe-filters and stored at 20 C until further analysis