However, pharmacological inhibition of autophagy has been found to enhance galangin-induced apoptosis and pyroptosis in human GBM cells, which proposes an effective therapeutic approach for GBM by a combination of galangin and an autophagy inhibitor [202]

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Ichikawa W, Takahashi T, Suto K, Sasaki Y, Hirayama R
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The electrophile reacts with proteins, DNA molecules, and phospholipids to exert toxic effects (dicarbonic stress) in the cells 5