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However, it would be interesting to assess CD38 expression in T cells from symptomatic familial AD individuals, and whether CD38 could also serve as an early diagnostic marker in sporadic AD, which accounts for 9095% of AD cases 1

17(1): p

Hence the physiological concentration in cells is about zero

188 Conversely, asprosin, interleukin-6 (IL-6), TNF-, and IL-12p70, which are predominantly secreted by visceral adipose tissue, 189 impair insulin signaling in muscle and liver and drive non-alcoholic fatty liver disease 190 via pro-inflammatory mechanisms