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Remarkably, forsythiaside can be considered a prodrug that, upon metabolism, will release a cinnamic acid derivative, which has a modulatory effect on neurotransmitters, as previously discussed

Macrophage activation syndrome in a patient with axial spondyloarthritis on adalimumab

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FTH1 alters intracellular iron homeostasis by influencing iron storage and release, and iron imbalance is a major trigger for ferroptosis (71,72)

Cardiac NAD+ Restoration NNMT-mediated NAD+ depletion impairs mitochondrial function, sirtuin activity, redox balance, and energy metabolism in cardiac tissue