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Current Opinion in Pharmacology , 9 , 6573

Sikiric P, Gojkovic S, Krezic I, Smoday IM, Kalogjera L, Zizek H, Oroz K, Vranes H, Vukovic V, Labidi M, Strbe S, Baketic Oreskovic L, Sever M, Tepes M, Knezevic M, Barisic I, Blagaic V, Vlainic J, Dobric I, Staresinic M, Skrtic A, Jurjevic I, Boban Blagaic A, Seiwerth S

Hypoxia promotes invasive growth by transcriptional activation of the met protooncogene

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This review describes the available FDA approved AD drugs, examples of drugs that have recently failed in clinical trials, and tentative reasons for these failures