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To estimate the association between metabolites and overall depression severity, we regressed AC levels on IDS-SR 30 total scores

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Acknowledgements The authors would like to thank the experimental apparatus and technical support provided by the Key Laboratory for Metabolic Diseases in Chinese Medicine, Nanjing University of Chinese Medicine

Decreased CrAT activity leads to increased levels of acyl-CoA, which leads to inhibition of multiple enzymatic processes involved in oxidative metabolism