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Therefore, further studies should be conducted to obtain more information on the heterogeneity of FreSHtracer-sorted GSH-high hES-MSCs at the single-cell level and to develop assessment criteria that can more clearly distinguish stem cells with high and low GSH levels

Benzofurazan sulfides for thiol imaging and quantification in live cells through fluorescence microscopy

7- Primary Ovarian Insufficiency One of the most challenging reproductive health conditions affecting women is Primary Ovarian Insufficiency (POI)

Furthermore, isolated MSCs undergo an age-dependent functional decline in stemness and undergo intrinsic alterations during in vitro culture, which also reduces their functions [9, 10]

J Biol Chem 273:2449124497 Solodkin A, Traub RJ, Gebhart GF (1992) Neuroscience 51:495499 Song P, Wu Y, Xu J, Xie Z, Dong Y, Zhang M, Zou MH (2007) Reactive nitrogen species induced by hyperglycemia suppresses Akt signaling and triggers apoptosis by upregulating phosphatase PTEN (phosphatase and tensin homologue deleted on chromosome 10) in an LKB1-dependent manner