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In a study by Desai and collaborators (161), it was shown that increased ROS levels can induce sperm DNA damage and even sperm death

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M., Istyastono, E., Bogaards, J

Antioxidants improve fertility by enhancing the activities of endogenous antioxidants (SOD, CAT, GPx, and GSH) or gonadotropins (luteinizing hormone, follicle-stimulating hormone, estradiol, and progesterone) and by inhibiting oxidative stress, lipid peroxidation, total oxidative stress, tumor necrosis factor-, and caspase proteins (Casp3 and Casp8)

These results indicate that the FSP1 GFP-P2A-BFP reporter cell line is heterozygous, expressing both untagged FSP1 and FSP1GFP, and that FSP1GFP and BFP are translated from the same transcript