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3.2.3.1 15q11-q13 The most common deletion/duplication syndrome associated with ASD phenotypes is the duplication syndrome of chromosome 15q11-q13.This region not only harbors the coding genes for GABA-A receptor 3 (GABRB3), 5 (GABRA5), and 3 (GABRG3) subunits but also serves as a genetic vulnerability hotspot due to its enrichment in low-copy repeats (LCRs)Deletions in the BP1-BP3 breakpoint regions are associated with ASD syndromes (64, 65)

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They concluded with justifiable excitement that " resveratrol exerts a neuroprotective effect on [a chemically-] induced Parkinson's disease rat model, and this protection is related to the reduced inflammatory reaction ." 208 As with green tea extracts, it appears that resveratrol's potential for preventing Parkinson's disease may reside in its multi-modal mechanism of action targeting oxidant stress, and inflammation, for example

A meta-analysis evaluated iodine supplementation during pregnancy in areas with mild-to-moderate iodine deficiency

New Drug,1999, 17, 271-284 19