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First, scopolamine-induced cognitive impairment in young rats used in McCoy 2013 and Benoist 2014 as a pharmacological model of cholinergic disruption of spatial learning, with Morris water maze as the primary behavioral readout

These alternative uses include the treatment of anxiety disorders, where gabapentin may have an anxiolytic effect, potentially benefiting individuals with generalized anxiety disorder or social anxiety disorder

A trifluoromethyl substituent provides a greater number of favorable Van der Waals contacts with the side chain than the chlorine substituent

Jan 21 2022;11(3)doi:10.3390/cells11030359 Schmauck-Medina T, Molire A, Lautrup S, et al